Genome-wide transcriptional profiling of HIV positive and negative adults with active tuberculosis, latent TB infection and other diseases - GSE37250_family (Illumina: HT12 V4)
Molecular Classification of AIDS-Related Lymphomas - GSE17189 (Affymetrix: HG-U133_Plus_2)
Gene Expression in Frontal Cortex in Major Depression and HIV - GSE17440 (Affymetrix: HG-U133_Plus_2)
Fatigue-related HIV disease gene-networks identified in CD14+ cells isolated from HIV-infected patients - GSE18468 (Affymetrix: human mitochondrial array)
Inflammation and macrophage activation in adipose tissue of HIV-infected patients under antiretroviral treatment - GSE19811 (Affymetrix: HG-U133A)
Blood Transcriptional Signature of hyperinflammation in HIV-associated Tuberculosis - GSE58411 (Illumina: HT12 V4)
Whole Blood Transcriptional Response to Early Acute HIV - GSE29429-GPL6947 (Illumina: HT12 V3)
Whole Blood Transcriptional Response to Early Acute HIV - GSE29429-GPL10558 (Illumina: HT12 V4)
CD4+ T Cell Decline is Predicted by Differential Expression of Genes in HIV seropositive patients - GSE10924 (Affymetrix: Human HG-Focus )
HIV-1 infection in human PBMCs in vivo - GSE2171 (Affymetrix: Human HG-Focus )
Gene expression analysis of PBMC from HIV and HIV/TB co-infected patients - GSE50834 (Illumina: HT12 V4)
Genome wide transcriptional profiling of HIV positive and negative children with active tuberculosis, latent TB infection and other diseases - GSE39941 (Illumina: HT12 V4)
The National NeuroAIDS Tissue Consortium Brain Gene Array: Two types of HIV-associated neurocognitive impairment - GSE35864 (Affymetrix: HG-U133_Plus_2)
Expression data from HAART interruption in HIV patients - GSE28177 (Affymetrix: HG-U133_Plus_2)
The Relationship between Virus Replication and Host Gene Expression in Lymphatic Tissue during HIV-1 Infection - GSE21589 (Affymetrix: HG-U133_Plus_2)
Microarray Analysis of Lymphatic Tissue Reveals Stage-Specific, Gene-Expression Signatures in HIV-1 Infection - GSE16363 (Affymetrix: HG-U133_Plus_2)
Expression data from CD11c+ mDCs in HIV infection - GSE42058 (Affymetrix: HG-U133_Plus_2)
Transcriptome analysis of HIV-infected peripheral blood monocytes - GSE50011 (Illumina: HT12 V4)
Transcriptome analysis of primary monocytes from HIV+ patients with differential responses to therapy - GSE52900 (Illumina: HT12 V3)
Longitudinal comparison of monocytes from an HIV viremic vs avirmeic state - GSE5220 (Affymetrix: HG-U133A)
Comparison of gene expression profiles of HIV-specific CD8 T cells from controllers and progressors - GSE24081 (Affymetrix: HG-U133A)
Comparative analysis of genomic features of human HIV-1 infection and primate models of SIV infection - GSE28128 (Illumina: Human V3 WG6)
Comparison of transcriptional profiles of CD4+ and CD8+ T cells from HIV-infected pateints and uninfected control group - GSE6740 (Affymetrix: HG-U133A)
Transcriptional profiling of CD4 T-cells in HIV-1 infected patients - GSE23879 (Illumina: Hu V3 Ref 8)
CD4+ T cell gene expression in virologically suppressed HIV-infected patients during Maraviroc intensification therapy - GSE56804 (Illumina: HT12 V4)
Genome wide mRNA expression correlates of viral control in CD4+T cells from HIV-1 infected individuals - GSE18233 (Illumina: Human V3 WG6)
Comparison of CD4+ T cell function between HIV-1 resistant and HIV-1 susceptible individuals (Affymetrix) - GSE14278 (Affymetrix: HG-U133_Plus_2)
Chronic CD4+ T cell Activation & Depletion in HIV-1 Infection: Type I Interferon-Mediated Disruption of T Cell Dynamic - GSE9927 (Affymetrix: HG-U133_Plus_2)
Differential Gene Expression in HIV-Infected Individuals Following ART - GSE44228 (Illumina: Human V3 WG6)
Differential Gene Expression of Soluble CD8+ T-cell mediated suppression of HIV replication in three older children - GSE23183 (Affymetrix: HG-U133_Plus_2)
Gene expression before HAART initiation predicts HIV-infected individuals at risk of poor CD4+ T cell recovery - GSE19087 (Illumina: Human V3 WG6)
Gene-expression profiling of HIV-1 infection and perinatal transmission in Botswana - GSE4124 (Affymetrix: HG-U133A)
Genome-wide analysis of gene expression in whole blood from HIV-1 progressors and non-progressors - GSE56837 (Illumina: Human V3 WG6)
Expression data from HIV exposed and uninfected women - GSE33580 (Affymetrix: HG-U133_Plus_2)
Genome-wide transcriptional profiling of HIV positive and negative adults with active tuberculosis, latent TB infection and other diseases - GSE37250_family
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Gene Symbol: SLC30A1
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| Description | Genome-wide transcriptional profiling of HIV positive and negative adults with active tuberculosis, latent TB infection and other diseases - GSE37250 |
| Purpose | The study aimed to define transcriptional signatures for detection of active TB (TB) compared to latent TB infection (LTBI) as well as to other diseases (OD) with similar clinical phenotypes in patients with and without HIV in two African adult populations. Transcriptional signatures were identified that distinguished active TB from LTBI, active TB from other diseases, and active TB from both LTBI and other diseases in HIV+/- patients. |
| Experimental Design | Adults were recruited from Cape Town, South Africa (n=300) and Karonga, Malawi (n=237) who were either HIV+ or HIV - with either active TB, LTBI or OD. Blood was collected into PAX gene tubes (PreAnalytiX). Total RNA integrity was assessed using an Agilent 2100 Bioanalyzer (Agilent, Palo Alto, CA). Labeled cRNA was hybridized to Illumina Human HT-12 Beadchips. Data were analysed in R. |
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